Nanocrystalline metallosilicate modified electrodes for the simultaneous, sensitive, and selective determination of riboflavin, rutin, and pyridoxine

Abstract

: Nanocrystalline metallosilicate modified glassy carbon electrodes were fabricated for the simultaneous determination of vitamins. Among these, nanocrystalline zirconosilicate exhibited the highest activity with a linear range from 30 nM–500 mM for riboflavin and 120 nM– 600 mM for rutin and pyridoxine. Sensitivity values of 2.8, 1.49, and 1.13 mA/mM cm2 and lower detection limits of 5 nM, 30 nM, and 30 nM for riboflavin, rutin, and pyridoxine, respectively, were found. The proposed sensor is stable and reproducible (RSD<3.5%). The analytical performance of this sensor was demonstrated in the pharmaceutical preparations (multivitamin tablets) with satisfactory recovery (97–103%).