Lewis Acid Catalyzed Annulation of Donor−Acceptor Cyclopropane and N‑Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H‑Furo[2,3‑c]pyrroles

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Title:	Lewis Acid Catalyzed Annulation of Donor−Acceptor Cyclopropane and N‑Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H‑Furo[2,3‑c]pyrroles
Authors:	Ghosh, A. Pandey, A.K. Banerjee, P.
Keywords:	Bioactivity Biochemistry Catalysis Potassium compounds Biologically active compounds Chemical equations Donor-acceptor cyclopropanes
Issue Date:	18-Nov-2016
Abstract:	An efficient MgI2-catalyzed annulation between donor−acceptor cyclopropane and N-tosylaziridinedicarboxylate to access highly substituted 2H-furo[2,3-c]pyrrole bearing two rings and four stereocenters, including one quaternary carbon stereocenter, has been developed. This methodology can be used for the synthesis of biologically active compounds like IKM-159. This work also offers an insight into the mechanism of the annulation process
URI:	http://localhost:8080/xmlui/handle/123456789/414
Appears in Collections:	Year-2015

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