Please use this identifier to cite or link to this item: http://dspace.iitrpr.ac.in:8080/xmlui/handle/123456789/4620
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSingh, A.-
dc.contributor.authorSingh, G.-
dc.contributor.authorKaur, N.-
dc.contributor.authorSingh, N.-
dc.date.accessioned2024-06-20T16:58:58Z-
dc.date.available2024-06-20T16:58:58Z-
dc.date.issued2024-06-20-
dc.identifier.urihttp://dspace.iitrpr.ac.in:8080/xmlui/handle/123456789/4620-
dc.description.abstractNitric oxide (NO) is a ubiquitous, gaseous, free radical signaling molecule which plays a key role in physiological and pathological processes. Literature reports revealed that the conventional methods such as colorimetry, electron paramagnetic resonance (EPR), electrochemical etc. to detect NO are costly, time consuming and lack resolution, particularly in aqueous or biological system. Thus, in this context, herein we have developed cova- lently linked biomass derived carbon quantum dots (CQDs) and naphthalimide based nano sensor system for FRET based ratiometric detection of nitric oxide (NO) in pure aqueous media. The CQDs derived from orange peels were characterized using UV–visible absorption, fluorescence spectroscopy, PXRD, TEM, FT-IR and zeta potential studies. Further, the obtained CQDs were functionalized with amine functionality, and subsequently linked with naphthalimide derivative (5) using terephthaldehyde through covalent bond formation. The conjugation of naphthalimide (5) and functionalized CQDs was studied using DLS, zeta potential, FT-IR and time resolved fluorescence spectroscopy. The excitation of developed nano sensor system at λex 360 nm results in fluorescence emission at λem 530 nm which establishes the FRET pair between the CQDs and naphthalimide unit. However, in the presence of NO, the observed FRET pair abolishes due to the cleavage of NO susceptible imine bond. The developed sensor demonstrates high selectivity towards NO with limit of detection (LOD) and limit ofen_US
dc.language.isoen_USen_US
dc.subjectNitrite detectionen_US
dc.subjectCarbon quantum dots (CQDs)en_US
dc.subjectFRETen_US
dc.subjectNitric oxideen_US
dc.subjectFluorescence spectroscopyen_US
dc.titleFabrication of FRET based nano sensor from biomass-derived fluorescent carbon quantum dots and naphthalimide for ratiometric detection of nitric oxide: To examine nitrite levels in meat samplesen_US
dc.typeArticleen_US
Appears in Collections:Year-2023

Files in This Item:
File Description SizeFormat 
full text.pdf3.68 MBAdobe PDFView/Open    Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.