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dc.contributor.authorKaur, G.-
dc.contributor.authorRaj, T.-
dc.contributor.authorSinghal, S.-
dc.contributor.authorKaur, N.-
dc.date.accessioned2017-10-23T06:53:33Z-
dc.date.available2017-10-23T06:53:33Z-
dc.date.issued2017-10-23-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/860-
dc.description.abstractIn the present report a dihydropyrimidine-based Biginelli compound 1 was engineered into stable organic nanoparticles via reprecipitation method. The organic nanoparticles, N1 acted as an efficient fluorescent nanosensor for selective detection of Ag (I) ions via fluorescence quenching with a detection limit of 7.9 nM. Furthermore, successful detection of spermidine (an important biogenic amine) was realized through an indirect metal ion mediated approach where the quenched fluorescence of complex, C was recovered with a red-shift on addition of spermidine. The lowest detection limitfor spermidine was found to be 3.2 nM. The nanosensor found applicability in a wide pH range from 3 to 12, which is appropriate for evaluation in environmental and physiological conditions. The selectivity for Ag (I) ions and spermidine was further confirmed with competitive binding studies which demonstrated no interference from other analytes. Moreover, real sample analysis established the practical applicability of the developed probes. The proposed strategy provides a facile, non-invasive, sensitive and economic platform for the estimation of Ag (I) ions in environmental samples (river water) and spermidine in biological samples (urine)en_US
dc.language.isoen_USen_US
dc.subjectBiginelli compounden_US
dc.subjectOff-on fluorescenceen_US
dc.subjectChemosensoren_US
dc.subjectSilver ionsen_US
dc.subjectSpermidineen_US
dc.titleTricyclic dihydropyrimidine-based multifunctional organic nanoparticles for detection of Ag (I) ions and spermidine: real-time applicationen_US
dc.typeArticleen_US
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