Development of electrochemical sensor for selective recognition of PO43− ions using organic nanoparticles of dipodal receptor in aqueous medium

Abstract

Dipodal Schiff's base based receptor (R1) was developed and characterized using 1H NMR, 13C NMR and mass spectroscopy and optimized its structure using DMol3 package. In order to evaluate the sensor activity in aqueous medium, R1was processed into organic nanoparticles (N1) using re-precipitation method. The prepared N1were characterized using techniques like dynamic light scattering (DLS) and transmission electron microscopy (TEM). To portray N1 as sensor, it was screened with various anions and found to respond selectively for PO43− ions with detection limit of 8.6 nM having a regression coefficient of 0.98912. The proposed sensor was successfully tested for real time analysis of biologically important phosphate molecules, with accuracy more than 95%.