A one-dimensional solid-state NMR approach for 14NH/14NH overtone correlation through 1 H/1 H mixing under fast MAS

Abstract

Homonuclear correlations are key to structural studies using solid-state NMR. In this contribution, using 14N overtone transition (OT) as a selective excitation approach, we propose a proton-detected onedimensional (1D) 14NOT/ 14NOT/ 1 H correlation solid-state NMR method mediated through 1 H/1 H mixing at fast magic angle spinning to achieve NH/NH proximities in naturally abundant samples. The proposed method is time efficient by a factor of B7.5 in comparison to the existing fundamental 14N frequencybased three-dimensional (3D) 14N/14N/1 H correlation method.