Abstract:
Herein, we report a p-toluenesulfonic
acid (PTSA) initiated mild and user-friendly ring
opening/domino ring opening cyclization reaction
(depends on substituent present in N-benzyl aniline)
of cyclopropane carbaldehyde and N-benzyl aniline
towards the formation of substituted 4-amino
butanal/2,3-dihydro-1H-benzo[b]azepine. The product dihydro-1H-benzo[b]azepine was also converted
into the corresponding tetrahydro-1H-benzo[b]azepine.