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Metal-free ring opening cyclization of cyclopropane carbaldehydes and n-benzyl anilines: an eco-friendly access to functionalized benzo[b]azepine derivatives

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dc.contributor.author Dey, R.
dc.contributor.author Banerjee, P.
dc.date.accessioned 2019-08-23T12:40:29Z
dc.date.available 2019-08-23T12:40:29Z
dc.date.issued 2019-08-23
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/1329
dc.description.abstract Herein, we report a p-toluenesulfonic acid (PTSA) initiated mild and user-friendly ring opening/domino ring opening cyclization reaction (depends on substituent present in N-benzyl aniline) of cyclopropane carbaldehyde and N-benzyl aniline towards the formation of substituted 4-amino butanal/2,3-dihydro-1H-benzo[b]azepine. The product dihydro-1H-benzo[b]azepine was also converted into the corresponding tetrahydro-1H-benzo[b]azepine. en_US
dc.language.iso en_US en_US
dc.subject Cyclopropane carbaldehyde en_US
dc.subject N-benzyl aniline en_US
dc.subject Metal-free ring opening cyclization en_US
dc.subject Benzo[b] azepine en_US
dc.title Metal-free ring opening cyclization of cyclopropane carbaldehydes and n-benzyl anilines: an eco-friendly access to functionalized benzo[b]azepine derivatives en_US
dc.type Article en_US


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