Abstract:
A metal-free strategy for the generation of N-centred radicals from
nitrosoarenes (activated by allylsulfones) via electron donor–acceptor
(EDA) complexes is reported. The EDA complex initiates a single electron
transfer (SET) process via diisopropylethylamine (iPr2NEt) or a Hantzsch
ester (HE). This mild and operationally simple protocol, initiated by the
formation of a C–N bond, can conclude to either isoxazolidine or
aziridine derivatives or can result in b-amino acid derivatives.