Transition-Metal-Free Regioselective Intermolecular Hydroamination of Conjugated 1,3-Dienes with Heterocyclic Amines

dc.contributor.author	Pradhan, S.
dc.contributor.author	Das, S.
dc.contributor.author	Kumar, G.
dc.contributor.author	Chatterjee, I.
dc.date.accessioned	2022-05-30T23:50:57Z
dc.date.available	2022-05-30T23:50:57Z
dc.date.issued	2022-05-31
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/3448
dc.description.abstract	The unique property of hexafluoroisopropanol (HFIP) enables the regioselective hydroamination of 1,3-dienes with nitrogen heterocycles in a Markovnikov manner in the presence of catalytic Brønsted acid. This transition-metal-free intermolecular hydroamination protocol is achieved under mild reaction conditions. The aggregation by HFIP and Brønsted acid helps to activate the terminal double bond regioselectively. Following the protonation of diene, the C-N bond formation is accomplished upon the involvement of heterocyclic amines.	en_US
dc.language.iso	en_US	en_US
dc.title	Transition-Metal-Free Regioselective Intermolecular Hydroamination of Conjugated 1,3-Dienes with Heterocyclic Amines	en_US
dc.type	Article	en_US