Light-mediated aminocatalysis: The dual-catalytic ability enabling new enantioselective route

Abstract

Over the last few decades, primary and secondary amines have been enormously used to trigger numerous valuable transformations. Likewise, modern-day chemistry has witnessed the potentiality of visible-light photoredox catalysis via single photoelectron transfer reactions. Recently, their synergistic effect has proved to be a crucial synthetic pillar, as several elegant protocols have their accessibility only under the cooperative action of this dual catalytic system. This catalytic system showcases a new green and sustainable synthetic approach which is advantageous from other methods. The emerging area of research demonstrates high efficiency of this dual-catalytic system to access the plethora of molecular complexity enantioselectively. This Review comprises several momentous developments that surfaced in the last five years in the field of photoredox-amine dual catalysis underpinning all types of synthetic transformations. By adapting the scope of each strategy, this Review will assist and inspire further development in this thriving field.