Lewis Acid Catalyzed Annulation of Donor−Acceptor Cyclopropane and N‑Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H‑Furo[2,3‑c]pyrroles

dc.contributor.author	Ghosh, A.
dc.contributor.author	Pandey, A.K.
dc.contributor.author	Banerjee, P.
dc.date.accessioned	2016-11-18T05:57:33Z
dc.date.available	2016-11-18T05:57:33Z
dc.date.issued	2016-11-18
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/414
dc.description.abstract	An efficient MgI2-catalyzed annulation between donor−acceptor cyclopropane and N-tosylaziridinedicarboxylate to access highly substituted 2H-furo[2,3-c]pyrrole bearing two rings and four stereocenters, including one quaternary carbon stereocenter, has been developed. This methodology can be used for the synthesis of biologically active compounds like IKM-159. This work also offers an insight into the mechanism of the annulation process	en_US
dc.language.iso	en_US	en_US
dc.subject	Bioactivity	en_US
dc.subject	Biochemistry	en_US
dc.subject	Catalysis	en_US
dc.subject	Potassium compounds	en_US
dc.subject	Biologically active compounds	en_US
dc.subject	Chemical equations	en_US
dc.subject	Donor-acceptor cyclopropanes	en_US
dc.title	Lewis Acid Catalyzed Annulation of Donor−Acceptor Cyclopropane and N‑Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H‑Furo[2,3‑c]pyrroles	en_US
dc.type	Article	en_US