Development of novel strategies for the construction of C-N and C–C bonds triggered by single-electron-transfer

Abstract

The entire work was focused on the application of two powerful state-of-the-art techniques, namely EDA (Electron donor acceptor) concept and Photoredox Catalysis, to develop novel synthetic protocols for the generation of electron-deficient NCRs (Nitrogen Centered Radicals) and CCRs (Carbon Centered Radicals), respectively, employing simple organic molecules as feedstock materials. In the field of radical chemistry, these two complementary modes of substrate activation have gained immense popularity in recent years. It also consists of a thorough investigation report on the reactivity of these radicals in the presence of various olefinic substrates (of mixed electron demands) as trapping reagents. Efficient trapping of these transiently formed radicals leads to the construction of new C–N or C–C bonds with the generation of a diverse array of heterocyclic scaffolds as well as hetero-atom containing linear chain molecules, which might help to surpass the ever-increasing demands to synthesize the complex molecular frameworks in the field of synthetic organic chemistry in a single step.