Abstract:
Three-membered carbocyclic and heterocyclic ring structures
are versatile synthetic building blocks in organic synthesis with
biological importance. Moreover, the inherent strain of these
three-membered rings leads to their ring-opening functionalization through C->C, C->N, and C O bond cleavage. Traditional
synthesis and ring-opening methods for these molecules
require the use of acid catalysts or transition metals. Recently,
electro-organic synthesis has emerged as a powerful tool for
initiating new chemical transformations. In this review, the
synthetic and mechanistic aspects of electro-mediated synthesis
and ring-opening functionalization of three-membered carboand heterocycles are highlighted