Browsing Year-2019 by Author "Agrewala, J. N."

Now showing items 1-6 of 6

Curdlan limits mycobacterium tuberculosissurvival through STAT-1 regulated nitric oxide production

Negi, S.; Pahari, S.; Das, D. K.; Khan, N.; Agrewala, J. N. (2021-08-30)

Host-directed therapies have emerged as an innovative and promising approach in tuberculosis (TB) treatment due to the observed limitations of current TB regimen such as lengthy duration and emergence of drug resistance. ...
A genomic analysis of mycobacterium immunogenum strain CD11-6 and its potential role in the activation of T cells against mycobacterium tuberculosis

Kaur, G.; Chander, A. M.; Kaur, G.; Maurya, S. K.; Nadeem, S.; Kochhar, R.; Bhadada, S. K.; Agrewala, J. N.; Mayilraj, S. (2021-08-22)

Background: Mycobacterium tuberculosis (Mtb) is an etiological agent of tuberculosis (TB). Tuberculosis is a mounting problem worldwide. The only available vaccine BCG protects the childhood but not adulthood form of TB. ...
Gut microbiota regulates mincle mediated activation of lung dendritic cells to protect against mycobacterium tuberculosis

Negi, S.; Pahari, S.; Bashir, H.; Agrewala, J. N. (2021-08-30)

Gut microbial components serve as ligand for various pattern recognition receptors (PRRs) present on immune cells and thereby regulates host immunity. Dendritic cells (DCs) are highly specialized innate cells involved in ...
Low prevalence of anti-xenobiotic antibodies among the occupationally exposed individuals is associated with a high risk of cancer

Sajid, M.; Agrewala, J. N. (2021-09-01)

Cancer is one of the major health problem globally, responsible for high morbidity and mortality. Exposure of humans to xenobiotics is associated with the development of cancer. Further, these xenobiotics may combine ...
Potential role of gut microbiota in induction and regulation of innate immune memory

Negi, S.; Das, D. K.; Pahari, S.; Nadeem, S.; Agrewala, J. N. (2021-08-30)

The gut microbiota significantly regulates the development and function of the innate and adaptive immune system. The attribute of immunological memory has long been linked only with adaptive immunity. Recent evidence ...
Predominance of M2 macrophages in gliomas leads to the suppression of local and systemic immunity

Vidyarthi, A.; Agnihotri, T.; Khan, N.; Singh, S.; Tewari, M. K.; Radotra, B. D.; Chatterjee, D.; Agrewala, J. N. (2021-08-14)

Glioblastoma is a highly prevalent and aggressive form of primary brain tumor. It represents approximately 56% of all the newly diagnosed gliomas. Macrophages are one of the major constituents of tumor-infltrating immune ...

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